Lyllana

Lyllana is Amneal's branded generic of Minivelle, approved in September 2020 and also sold unbranded. ASHP lists all five strengths as available, which makes it one of the better-supplied twice-a-week patches on paper.

On paper is the point. Medfinder's checks over the last 30 days found Lyllana in stock in about 1% of them (Medfinder). Those checks are made for people who couldn't find it, so they read low, but they show "available" at the maker doesn't mean on your pharmacy's shelf.

Made by
Amneal
Changed
Twice a week
Strengths
0.025 mg, 0.0375 mg, 0.05 mg, 0.075 mg, 0.1 mg
FDA approval
ANDA 211396
Medfinder in-stock rate
1% of 605 checks

Status by strength

Patch0.025 mg0.0375 mg0.05 mg0.075 mg0.1 mg
LyllanaAmneal · twice a week AvailableAvailableAvailableAvailableAvailable
  • Available
  • Limited
  • Short
  • Discontinued
  • No data

Statuses checked October 18, 2026 against each row's source. We re-check every week.

Each strength in detail

0.025 mg (available) · 0.0375 mg (available) · 0.05 mg (available) · 0.075 mg (available) · 0.1 mg (available)

Any change of brand, strength or form is a decision for your prescriber, and your pharmacist can check what they can order.

Sources

  1. Lyllana label, DailyMed, Amneal, May 15, 2024.
  2. Drug Shortage Detail: Estradiol Transdermal System, ASHP, August 12, 2026.
  3. Estradiol shortage tracker, Medfinder, October 18, 2026.
  4. Orange Book: Approved Drug Products with Therapeutic Equivalence Evaluations (data files), FDA, October 9, 2026.