0.1 mg estradiol patches

0.1 mg a day (100 mcg on a Canadian box) is made by 13 US products and 2 in Canada. Here is each one, best supplied first.

In the US

13 products: 2 short, 2 limited, 5 available, 3 with no data, 1 discontinued.

  • Climara Bayer · Changed once a week ASHP lists it as available. Bayer says one Climara dose, which it hasn't named, faces supply constraints until early 2027. ASHP, October 18, 2026. Available
  • Estradiol twice-weekly patch (Mylan, Minivelle type) Mylan (Viatris) · Changed twice a week ASHP lists it as available. ASHP, October 18, 2026. Available
  • Estradiol twice-weekly patch (Mylan, Vivelle-Dot type) Mylan (Viatris) · Changed twice a week ASHP lists it as available. ASHP, October 18, 2026. Available
  • Estradiol weekly patch (Mylan) Mylan (Viatris) · Changed once a week ASHP lists every strength as available. ASHP, October 18, 2026. Available
  • Lyllana Amneal · Changed twice a week ASHP lists every strength as available. ASHP, October 18, 2026. Available
  • Estradiol twice-weekly patch (Noven) Noven · Changed twice a week Intermittent back order with weekly releases, because of higher demand, Noven says. ASHP, October 18, 2026. Limited
  • Estradiol twice-weekly patch (Zydus) Zydus · Changed twice a week On allocation. Zydus gave no reason. ASHP, October 18, 2026. Limited
  • Estradiol twice-weekly patch (Sandoz) Sandoz · Changed twice a week Not on ASHP's shortage bulletin either way, and the maker hasn't said. ASHP, October 18, 2026. No data
  • Estradiol weekly patch (Zydus) Zydus · Changed once a week Not on ASHP's shortage bulletin either way, and the maker hasn't said. ASHP, October 18, 2026. No data
  • Vivelle-Dot Sandoz · Changed twice a week Not on ASHP's shortage bulletin either way, and the maker hasn't said. ASHP, October 18, 2026. No data
  • Dotti Amneal · Changed twice a week On back order. Amneal cannot estimate a release date. ASHP, October 18, 2026. Short
  • Estradiol weekly patch (Sandoz) Sandoz · Changed once a week On back order. Sandoz cannot estimate a release date. ASHP, October 18, 2026. Short
  • Minivelle Noven · Changed twice a week ASHP says the Minivelle brand was discontinued in February; Noven still sells the same patch unbranded. ASHP, October 18, 2026. Discontinued

In Canada

2 products: 1 short, 1 limited.

  • Sandoz Estradiol Derm Sandoz Canada · Changed twice a week · DIN 02246969 Available, but not every pharmacy has stock (Toronto Star). Toronto Star, October 18, 2026. Limited
  • Estradot Sandoz Canada · Changed twice a week · DIN 02244002 Out of stock since August 3, the Toronto Star reports. Sandoz says demand it calls "unprecedented" cannot be fully met yet. Toronto Star, October 18, 2026. Short

What menopause societies list as similar doses

When a patch can't be found, prescribers sometimes move people to a gel or tablets. Three menopause societies publish tables of roughly similar doses. They don't fully agree, all three call the figures approximate, and only a prescriber can make the change.

Published byGelGel sachetTablet
Canadian Menopause SocietyCanada, "High" dose EstroGel 4 pumpsDivigel 1.0 mg × 2Estradiol 3 to 4 mg
Australasian Menopause SocietyAustralia, "High" dose Estrogel 3 or 4 pumpsSandrena 1.5 mgNot given
British Menopause SocietyUK Oestrogel 4 measuresNot givenNot given

Any change of brand, strength or form is a decision for your prescriber, and your pharmacist can check what they can order.

The full tables, and the gels, sprays and tablets sold in the US

Sources

  1. Drug Shortage Detail: Estradiol Transdermal System, ASHP, August 12, 2026.
  2. "If this were Viagra, Canada would call in the army," but it's estrogen, and it keeps running out, Toronto Star, October 12, 2026.
  3. Drug Shortages Canada (Health Product Shortages), Drug Shortages Canada, October 18, 2026.
  4. Systemic Menopause Hormone Therapy (MHT) Equivalency Table, Canadian Menopause Society, January 1, 2025.
  5. AMS Guide to MHT/HRT Doses, Australia, Australasian Menopause Society, December 20, 2024.
  6. HRT preparations and equivalent alternatives, British Menopause Society, August 1, 2026.