Minivelle

Minivelle is Noven's small twice-a-week patch. ASHP's shortage bulletin says the Minivelle brand was discontinued in February, while Noven's unbranded version of the same patch is still sold. That version is on intermittent back order with weekly releases, which Noven puts down to higher demand.

Two other makers have patches the FDA rates against Minivelle: Mylan, whose version ASHP lists as available in every strength, and Amneal, whose Lyllana is also listed as available. Mylan's patch is larger than Minivelle at each strength.

Made by
Noven
Changed
Twice a week
Strengths
0.025 mg, 0.0375 mg, 0.05 mg, 0.075 mg, 0.1 mg
FDA approval
NDA 203752
Medfinder in-stock rate
3% of 102 checks

Status, with the patches rated against it

Patch0.025 mg0.0375 mg0.05 mg0.075 mg0.1 mg
MinivelleNoven · twice a week DiscontinuedDiscontinuedDiscontinuedDiscontinuedDiscontinued
Noven twice-weeklyNoven · twice a week LimitedLimitedLimitedLimitedLimited
Mylan twice-weekly (MV)Mylan (Viatris) · twice a week AvailableAvailableAvailableAvailableAvailable
LyllanaAmneal · twice a week AvailableAvailableAvailableAvailableAvailable
  • Available
  • Limited
  • Short
  • Discontinued
  • No data

Statuses checked October 18, 2026 against each row's source. We re-check every week.

Each strength in detail

0.025 mg (discontinued) · 0.0375 mg (discontinued) · 0.05 mg (discontinued) · 0.075 mg (discontinued) · 0.1 mg (discontinued)

Any change of brand, strength or form is a decision for your prescriber, and your pharmacist can check what they can order.

Sources

  1. Minivelle label, DailyMed, Noven, July 31, 2026.
  2. Estradiol transdermal system (authorized generic of Minivelle) label, DailyMed, Noven, April 5, 2024.
  3. Estradiol transdermal system, twice weekly (ANDA 206685) label, DailyMed, Mylan, June 23, 2025.
  4. Lyllana label, DailyMed, Amneal, May 15, 2024.
  5. Drug Shortage Detail: Estradiol Transdermal System, ASHP, August 12, 2026.
  6. Orange Book: Approved Drug Products with Therapeutic Equivalence Evaluations (data files), FDA, October 9, 2026.
  7. Estradiol shortage tracker, Medfinder, October 18, 2026.