0.05 mg estradiol patches

0.05 mg a day (50 mcg on a Canadian box) is made by 13 US products and 3 in Canada. Here is each one, best supplied first.

In the US

13 products: 4 limited, 5 available, 3 with no data, 1 discontinued.

  • Climara Bayer · Changed once a week ASHP lists it as available. Bayer says one Climara dose, which it hasn't named, faces supply constraints until early 2027. ASHP, October 18, 2026. Available
  • Dotti Amneal · Changed twice a week ASHP lists it as available. ASHP, October 18, 2026. Available
  • Estradiol twice-weekly patch (Mylan, Minivelle type) Mylan (Viatris) · Changed twice a week ASHP lists it as available. ASHP, October 18, 2026. Available
  • Estradiol weekly patch (Mylan) Mylan (Viatris) · Changed once a week ASHP lists every strength as available. ASHP, October 18, 2026. Available
  • Lyllana Amneal · Changed twice a week ASHP lists every strength as available. ASHP, October 18, 2026. Available
  • Estradiol twice-weekly patch (Mylan, Vivelle-Dot type) Mylan (Viatris) · Changed twice a week On intermittent back order; Viatris releases supply as it becomes available. ASHP, October 18, 2026. Limited
  • Estradiol twice-weekly patch (Noven) Noven · Changed twice a week Intermittent back order with weekly releases, because of higher demand, Noven says. ASHP, October 18, 2026. Limited
  • Estradiol twice-weekly patch (Zydus) Zydus · Changed twice a week On allocation. Zydus gave no reason. ASHP, October 18, 2026. Limited
  • Estradiol weekly patch (Sandoz) Sandoz · Changed once a week On allocation: pharmacies get a set share of what is made. ASHP, October 18, 2026. Limited
  • Estradiol twice-weekly patch (Sandoz) Sandoz · Changed twice a week Not on ASHP's shortage bulletin either way, and the maker hasn't said. ASHP, October 18, 2026. No data
  • Estradiol weekly patch (Zydus) Zydus · Changed once a week Not on ASHP's shortage bulletin either way, and the maker hasn't said. ASHP, October 18, 2026. No data
  • Vivelle-Dot Sandoz · Changed twice a week Not on ASHP's shortage bulletin either way, and the maker hasn't said. ASHP, October 18, 2026. No data
  • Minivelle Noven · Changed twice a week ASHP says the Minivelle brand was discontinued in February; Noven still sells the same patch unbranded. ASHP, October 18, 2026. Discontinued

In Canada

3 products: 1 short, 2 with no data.

  • Estradot Sandoz Canada · Changed twice a week · DIN 02244000 No source we could read gives a current status. Check the DIN on Drug Shortages Canada. Drug Shortages Canada, October 18, 2026. No data
  • Sandoz Estradiol Derm Sandoz Canada · Changed twice a week · DIN 02246967 No source we could read gives a current status. Check the DIN on Drug Shortages Canada. Drug Shortages Canada, October 18, 2026. No data
  • Climara (Canada) Bayer Inc. · Changed once a week · DIN 02231509 Short because of increased demand, Bayer says. Expected back: December 2026, Bayer expects. Toronto Star, October 18, 2026. Short

What menopause societies list as similar doses

When a patch can't be found, prescribers sometimes move people to a gel or tablets. Three menopause societies publish tables of roughly similar doses. They don't fully agree, all three call the figures approximate, and only a prescriber can make the change.

Published byGelGel sachetTablet
Canadian Menopause SocietyCanada, "Standard" dose EstroGel 1 to 2 pumpsDivigel 1.0 mgEstradiol 1 mg
Australasian Menopause SocietyAustralia, "Medium" dose Estrogel 2 pumpsSandrena 1 mgEstradiol 2 mg
British Menopause SocietyUK Oestrogel 2 measuresSandrena 1 mgNot given

Any change of brand, strength or form is a decision for your prescriber, and your pharmacist can check what they can order.

The full tables, and the gels, sprays and tablets sold in the US

Sources

  1. Drug Shortage Detail: Estradiol Transdermal System, ASHP, August 12, 2026.
  2. "If this were Viagra, Canada would call in the army," but it's estrogen, and it keeps running out, Toronto Star, October 12, 2026.
  3. Drug Shortages Canada (Health Product Shortages), Drug Shortages Canada, October 18, 2026.
  4. Systemic Menopause Hormone Therapy (MHT) Equivalency Table, Canadian Menopause Society, January 1, 2025.
  5. AMS Guide to MHT/HRT Doses, Australia, Australasian Menopause Society, December 20, 2024.
  6. HRT preparations and equivalent alternatives, British Menopause Society, August 1, 2026.